METABOLIC SYNDROME PROGRAMMING AND REPROGRAMMING: MECHANISTIC ASPECTS OF OXIDATIVE STRESS


Novel Percutaneous Areola Reduction

Summary:.We present a novel percutaneous areola reduction technique that, to our knowledge, has never been used or published in the past.This technique is Tortilla Servers a useful solution to the downsides of the Cot current most commonly used technique for areola reductions that uses a circumareolar incision.Our current technique utilizes a percu

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Geranylgeranyl diphosphate synthase inhibitor and proteasome inhibitor combination therapy in multiple myeloma

Abstract Background Multiple myeloma (MM) remains an incurable malignancy, despite the advent of therapies such as proteosome inhibitors (PIs) that disrupt protein homeostasis and induce ER stress.We have pursued inhibition of geranylgeranyl diphosphate synthase (GGDPS) as a novel mechanism by which to target protein homeostasis in MM cells.GGDPS i

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